Histological Classification of Cancer and Precancer of the Oral Mucosa |
1. Carcinomas
- Squamous cell carcinoma
- Verrucous cell carcinoma
- Basaloid squamous cell carcinoma
- Adenoid squamous cell carcinoma
- Spindle cell carcinoma
- Adenosquamous carcinoma
- Undifferentiated carcinoma
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2. Benign lesions capable of microscopically resembling oral squamous cell carcinoma and oral verrucous carcinoma
- Papillary hyperplasia
- Granular cell tumor
- Discoid lupus erythematosus
- Median rhomboid glossitis
- Keratoacanthoma
- Necrotizing sialometaplasia
- Juxtaoral organ of Chievitz
- Chronic hyperplastic candidiasis
- Verruciform xanthoma
- Verruca vulgaris
- Condyloma acuminatum
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3. Precancerous lesions (Clinical classification)
- Leukoplakia
- Erythroplakia
- Palatal keratosis associated with reverse smoking
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4. Precancerous lesions (Histological classification)
- Squamous epithelial dysplasia
- Squamous cell carcinoma in situ
- Solar keratosis
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5. Benign lesions capable of resembling oral precancerous lesions
- White lesions resembling leukoplakia
- red lesions resembling erythroplakia
- Focal epithelial hyperplasia
- Reactive and regenerative atypia
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6. Precancerous conditions
- Sideropenic dysphagia
- Lichen planus
- Oral submucous fibrosis
- Syphilis
- Discoid lupus erythematosus
- Xeroderma pigmentosum
- Epidermolysis bullosa
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