Pharmacology MCQs - Drugs acting on CVS, GIT and Respiratory Systems

NOTE: It has been proved that you will retain more of what MCQs you study if you study first and then test yourself immediately. For that, First Watch this Video and Study all the MCQs and then Test yourself by taking the Quiz below.

# Antacid drug that typically causes diarrhoea is:
A. Sodium bicarbonate
B. Magnesium hydroxide
C. Calcium carbonate
D. Aluminum hydroxide

# The antiulcer agent which detaches and kills H. pylori organism and prevent relapses is:
A. Colloidal bismuth
B. Pirenzepine
C. Misoprostol
D. Sucralfate



# Centrally acting sympatholytic agent used as antihypertensive agent:
A. Propranolol
B. Clonidine
C. Prazosin
D. Phenoxybenamine

# Correct about inotropic agent is:
A. Adrenaline increases renal perfusion
B. Dobutamine cause peripheral vasoconstriction
C. Dopamine causes increased blood flow
D. Noradrenaline causes hepatic vasodilation

# About heparin, the true is:
A. Mixture of sulphated polypeptide
B. Known to cause idiopathic thrombocytosis
C. Half-life is 90 min
D. Decrease action of prothrombin II

# Which of the following is a protective drug in the management of gastric and duodenal ulcers?
A. H2 antihistamines
B. NaHCO3
C. Famotidine
D. Carbenoxolone

# Which of the following statements regarding nitroglycerin is true?
A. The effect is more pronounced in venous
B. High membrane permeability
C. Poorly suited for oral administration
D. All of the above

# Which one of these anti-hypertensives are contraindicated in pregnancy?
A. Hydralazine
B. a-Methyldopa
C. Nifedipine
D. Enalapril

# Following inhibits Cytochrome P450:
A. Cimetidine
B. Famotidine
C. Ranitidine
D. All of the above

# All of the following are predominant arteriolar dilators Except:
A. Sodium nitroprusside
B. Hydralazine
C. Nifedipine
D. Nitrates

# Which of the following is an ACE inhibitor?
A. Saralosin
B. Diltiazem
C. Captopril
D. Spironolactone

# Which of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of reflux?
A. Ondansetron
B. Metoclopramide
C. Sodium citrate
D. Atropine

# Omeprazol is used in the treatment of:
A. Peptic ulcer
B. Amoebiasis
C. Malaria
D. Cholera

# All of the following drugs reduce the gastric secretion EXCEPT:
A. Ranitidine
B. Sucralfate
C. Misoprostol
D. Pantoprazole

# Long acting B-2 agonist is:
A. Albuterol
B. Salmeterol
C. Pributerol
D. Orciprenaline

# Drug not requiring dose adjustment in renal disease is:
A. Aminoglycoside
B. Vancomycin
C. Calcium channel blocker
D. Metronidazole

# Which one of the following drugs is most commonly employed in an attack of angina pectoris.
A. Sodium nitrate
B. Epinephrine
C. Nitroglycerine
D. Isosorbide dinitrate

# All the given drugs may be useful in acute exacerbation of bronchial asthma EXCEPT:
A. Cromolyn sodium
B. Hydrocortisone
C. Salbutamol
D. Ipratropium

# Salbutamol is used in:
A. Cardiac asthma
B. Bronchial asthma
C. Pulmonary edema
D. Cor pulmonale

# Kaolin Pectose is:
A. Mummifying agent
B. Anticoagulant
C. Counter irritant
D. Antidiarrhoeal

# One of the following is not an antiemetic:
A. Chlorpromazine
B. Digitoxin
C. Metoclopramide
D. Scopolamine

# Omeprazole is a:
A. Antihistamine
B. Proton pump inhibitor
C. Ulcer protective
D. Ulcer healing agent

# Infliximab (systemtic) is used in:
A. Chron's disease (treatment)
B. To reduce the number of draining enterocutaneous fistula in patients with fistulizing Chron's disease
C. Rheumatoid arthritis (treatment)
D. All of the above

# All of the given drugs are positive inotropes EXCEPT:
A. Dopamine
B. Dobutamine
C. Digoxin
D. Doxepin

# Which is not antiemetic?
A. Domperidone
B. Pentazocine
C. Cyclizine
D. Ondansetron

# Ipratropium bromide is used for:
A. Renal colic
B. Organophosphorous poisoning
C. Bronchial asthma
D. Miosis

# Beta-blocker with additional alpha blocking property is:
A. Propranolol
B. Timolol
C. Metoprolol
D. Labetalol

# Which one of the following is NOT true of angiotensin converting enzyme (ACE) inhibitor:
A. May cause hyperkalemia in diabetic patients
B. Contraindicated in pregnancy
C. Contraindicated in diabetic nephropathy
D. NSAIDs may impair its hypotensive effect

# A young lady taking Rifampicin and OCP together become pregnant, most probable cause is:
A. Rifampicin causes hepatic enzyme induction and increase metabolism of OCPs
B. Decreased absorption of OCPs
C. Obstruction of fallopian tubes
D. Increased excretion of OCPs

# Which one is not converted to an active metabolite?
A. Quinapril
B. Fosinopril
C. Benzopril
D. Lisinopril

# Which of following is not true about ACE inhibitors?
A. can be used in asthmatics
B. Increase quality of life
C. Postural hypotension is seen
D. Na level decrease

# Which one of the following sympathomimetic agents is the most potent bronchodilator?
A. Amphetamine
B. Norepinephrine
C. Isoproterenol
D. Phenylephrine

# Which of the following is antiasthmatic?
A. Histamine
B. Salbutamol
C. Acetylcholine
D. Serotonin

# Beta 2 adrenergic receptor stimulating drugs are used in:
A. Bronchial Asthma
B. Cardiac asthma
C. Hypertension
D. Angina petoris

# Alpha blockers are used in all EXCEPT:
A. Pheochromocytoma
B. Migraine
C. Thyrotoxicosis
D. Secondary shock

# Bradycardia is most commonly treated with of the following drugs?
A. Epinephrine
B. Atropine
C. A diuretic
D. A potent vasodilator

# Each of the following is correct regarding the treatment of diarrhoea except:
A. Kaolin has marginal therapeutic effect
B. Opioids delay the passage of gut contents by decreasing peristalsis and increasing intestinal segmentation
C. Loperamide has high abuse potential
D. Diphenoxylate may cause respiratory depression on administration

# All of the following about antiemetic drugs are true EXCEPT:
A. Domperidone blocks the D2 receptors in CTZ upper gut
B. Domperidone causes dystonia
C. Ondansetron acts on selective 5-HT3 receptors
D. Ondansetron may cause vomitting by effecting the cytotoxic antigen receptors

# Magnesium and aluminium are added in antacid because:
A. Mg causes constipation, Al causes diarrhea
B. Mg causes Diarrhoea, Al causes constipation
C. Mg act as buffering agent and Al antagonize its action
D. Both increase gastric motility

# Which one of the following drugs is not contraindicated in bronchial asthma?
A. Morphine
B. Propranolol
C. Stropine
D. Nitroglycerine

# Bronchospasm can be precipitated by:
A. Adrenaline
B. Propranolol
C. Atropine
D. Salbutamol

# The following drugs are useful in hypertension EXCEPT:
A. Calcium channel blockers
B. Alpha methyl dopa
C. Beta blockers
D. Pentoxifylline

# The potent anti-arrhythmic drug which has little negative inotropic effect valuable in patients with poor left ventricular function:
A. Amlodipine
B. Bidoprolo
C. Amiodarone
D. Digoxin

# Beta blockers are contraindicated in:
A. Angina pectoris
B. Cardiac arrhythmia
C. Cardiac failure
D. Myocardial infarction

# Quinidine is used to treat:
A. Hypertension
B. Angina
C. Atrial fibrillation
D. Congestive heart failure

# Action of nitroglycerine is:
A. Direct action on smooth muscle
B. Slows SA node conductivity
C. Blocks arrhythmia
D. Increases perfusion to heart

# Which of the following is not an antimigraine agent?
A. Flunarizine
B. Divalprox sodium
C. Zonisamide
D. Propranolol

# Which of the following antihypertensive agents is most likely to cause an exaggerated response to an injected catecholamine?
A. Propranolol
B. Hydralazine
C. A thiazide diuretic
D. Guanethidine

# All of the following drugs are useful in treatemnt of hypertension except:
A. Ephedrine
B. Reserpine
C. Methyldopa
D. Thiazole diuretics

# Isosorbide 5- mononitrate is preferred because:
A. Less tolerance develops
B. Sublingual absorption is better
C. Longer duration of action
D. Direct coronary vasodilatory action is more

# Alpha blocker used as an antihypertensive agent is:
A. Alpha methyl dopa
B. Prazosin
C. Clonidine
D. Propranolol

# Hypokalemia is seen in therapy with:
A. Digitalis
B. Ibuprofen
C. Corticosteroids
D. Diazepam

# Which of the following is not caused by Furosemide?
A. Hypokalemic
B. Hyperuricemia
C. Hypercalcemia
D. Hyponatremia

# Morphine is a:
A. Sedative and alkaloid
B. Anti-hypertensive and diuretic
C. Only A
D. Only B

# Heroin, an addict drug contains:
A. Acetyl salicylic acid
B. Acetyl morphine
C. Pentazocine
D. Propoxyphene

# The mechanism of action of sodium nitroprusside is:
A. Increases cAMP
B. Direct vasodilator
C. Calcium channel blocker
D. Block the sympathetic flow at hypothalamus

# Diuretics cause loss of:
A. Sodium
B. Calcium
C. Potassium
D. Iron

# Mechanism of action of nifedipine is:
A. It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure
B. Nifedipine depresses the SA node thus decreasing myocardial excitability
C. Mainly depression of A-V conduction
D. Decrease cardiac output thus decreasing load on myocardium