MCQs on Carbohydrate Metabolism - Biochemistry MCQs

# The rate of absorption of sugars by the small intestine is highest for:
A. Pentoses
B. Disaccharides
C. Polysaccharides
D. Hexoses

# Which one of the following enzymes use NADP as conenzyme?
A. Glyceraldehyde 3 phosphate dehydrogenase
B. Lactate dehydrogenase
C. Glucose-6-phosphate dehydrogenase
D. Beta hydroxy acyl coA dehydrogenase



# Which of the following is not a polymer of glucose?
A. Glycogen
B. Cellulose
C. Amylase
D. Inulin

# An essential for the conversion of glucose to glycogen in liver is:
A. UTP
B. GTP
C. Pyruvate kinase
D. Guanosine

# Glycogen synthesis is increased by:
A. Cortisone
B. Insulin
C. GH
D. Epinephrine

# Major contribution towards gluconeogenesis is by:
A. Lactate
B. Glycerol
C. Ketones
D. Alanine

# Gluconeogenesis occurs in the liver and ________.
A. Kidney
B. Muscle
C. Heart
D. Fat

# The tissue with highest glycogen content (mg/100gm) is:
A. Liver
B. Muscle
C. Kidneys
D. Testes

# Adrenaline acts on which enzyme in glycogenolysis?
A. Glucokinase
B. Hexokinase
C. Phosphorylase
D. Glucose diphosphate

# Glucose can be synthesized from all except:
A. Amino acids
B. Glycerol
C. Acetoacetate
D. Lactic acid

# Insulin acts on which enzyme in glycolysis?
A. Glucokinase
B. Hexokinase
C. Glucose-6-phosphatase
D. Adenylate kinase

# The first product of glycogenolysis is:
A. Glucose-6-phosphate
B. Glucose 1,6 diphosphate
C. Glucose-1-phosphate
D. Fructose-1-phosphate

# The compound that can give rise to glucose by gluconeogenesis is:
A. Acetyl coA
B. Lactate
C. Palmitic acid
D. Fructose

# During conversion of glycerol to pyruvic acid, the first glycolytic intermediate to form is:
A. 2 phosphoglyceric acid
B. 3 phosphoglyceric acid
C. 3 phosphoglyceric acid
D. Dihydroxyacetone phosphate

# Which of the following statements is TRUE?
A. The hydrolysis of lactose yields glucose and galactose
B. The hydrolysis of maltose yields glucose and fructose
C. The hydrolysis of sucrose yields only glucose
D. All of the above statements are true

# All of the following are the substrates for gluconeogenesis except:
A. Alanine
B. Oleic acid
C. Glycerol
D. Tryptophan

# Enzymes concerned with the citric acid cycle are found in the :
A. Nucleus
B. Ribosomes
C. Mitochondria
D. Nonparticulate cytoplasm

# Kreb's cycle occurs in :
A. Aerobic conditions
B. Anaerobic conditions
C. Microaerophilic conditions
D. Both aerobic and anaerobic conditions

# In TCA cycle, substrate level phosphorylation take place in:
A. Alpha ketoglutarate to succinyl coA
B. Succinyl coA to succinate
C. Succinate to fumarate
D. Oxaloacetate to citrate

# Which acid is formed in the citric acid cycle?
A. Oxaloacetic acid
B. Glutamic acid
C. Nitric acid
D. Butyric acid

# Cane sugar is:
A. Glucose
B. Sucrose
C. Fructose
D. Maltose

# The main enzyme responsible for the activation of Xenobiotics is:
A. Cytochrome P-450
B. Glutathione S-transferase
C. NADPH cytochrome P-450 reductase
D. Glucuronyl transferase

# The conversion of glucose-6-phosphate to fructose-6-phosphate is an example of which of the following reactions?
A. Phosphate transfer
B. Isomerization
C. Dehydration
D. Aldol cleavage

# What high energy phosphate compound is formed in the citric acid cycle through substrate level phosphorylation?
A. ATP
B. TTP
C. ITP
D. GTP

# Which of the following is abnormal constituent of urine:
A. Glucose
B. Creatine
C. Urea
D. None of the above

# Which of the following is a non reducing sugar?
A. Glucose
B. Maltose
C. Lactose
D. Sucrose

# Which one of the following is a monosaccharide?
A. Maltose
B. Sucrose
C. Fructose
D. Starch

# The end product of glycolysis under anaerobic conditions is:
A. Lactic acid
B. Pyruvic acid
C. Acetoacetic acid
D. Oxaloacetic acid

# In prolonged starvation, the main energy source of brain is:
A. Glucose
B. Ketone bodies
C. Fructose
D. Fatty acids

# The enzyme involved in the first committed step of glycolysis is:
A. Phosphofructokinase
B. Glucose-6-phosphatase
C. Hexokinase
D. Enolase

# Renal threshold for glucose is:
A. 80 mg%
B. 100 mg%
C. 180 mg/dL
D. 200 mg%

# Which one of the following is correctly matched?
A. Isocitrate to oxalosuccinate - 1 ATP is formed
B. Succinyl coA to succinate - 1 ATP is formed
C. Succinate to fumarate - 1 ATP is formed
D. Malate to oxaloacetate - 1 ATP is formed

# In TCA cycle, which is first formed?
A. Isocitrate
B. Citrate
C. Succinate
D. Fumarate

# In TCA cycle, substrate level phosphorylation occurs at:
A. Succinate dehydrogenase
B. Malonate reaction
C. Thiokinase
D. None of the above

# Kreb's cycle does not occur in:
A. Muscle
B. RBC
C. Heart
D. All of the above

# In TCA cycle, citrate is converted into ________ after losing a molecule of H2O.
A. Isocitrate
B. Cis-Aconitate
C. Oxaloacetate
D. Glutarate

# Which metabolite of TCA cycle is used in detoxification of ammonia in brain?
A. Alpha ketoglutarate
B. Ornithine
C. Oxaloacetate
D. Glycine

# Inhibition of glycolysis by Oxygen is known as:
A. Muni effect
B. Pasteur effect
C. Hill reaction
D. Gluconeogenesis

# Phosphofruktokinase is the key enzyme of:
A. Glycolysis
B. Gluconeogenesis
C. Beta oxidation
D. TCA cycle

# In glycolysis, ATP is produced by the following enzyme:
A. Hexokinase
B. Phosphoglycerate kinase
C. Enolase
D. Phosphohexose isomerase

# An enzyme not involved in glycolysis is:
A. Enolase
B. Phosphoglyceromutase
C. Aldolase
D. Glycerophosphate dehydrogenase

# The main pathways of metabolism in brain are:
A. Glycolysis and Citric acid cycle
B. Glucogenolysis and Gluconeogenesis
C. Embden-Meyerhof pathway and HMP shunt pathway
D. Glycogenolysis and citric acid cycle

# McArdles disease is due to the deficiency of:
A. Glucose-1-phosphatase
B. Glucose 1,6 diphosphatase
C. Glucose-6-phosphatase
D. Myophosphorylase

# 1 molecule of glucose forms ______ molecules of pyruvate.
A. 1
B. 2
C. 3
D. 5

# In which type of glycogen storage disease is hyperuricemia a feature?
A. I
B. II
C. III
D. IV

# Galactosemia is commonly due to deficiency of:
A. Galactose-1-phosphate uridyl transferase
B. Galactose-1-phosphatase
C. Glucose-1-phosphatase
D. Glucose-6-phosphatase

# Sites where HMP shunts can occur include:
A. Liver
B. Lactating mammary gland
C. Testes
D. All of the above

# Blood glucose levels cannot be augmented by mobilization of muscle oxygen due to lack of:
A. G-6-P Dehydrogenase
B. G-6-phosphatase
C. Aldolase
D. Glucokinase

# Glucose-6-phosphatase deficiency is seen in:
A. Pompei's disease
B. von Gierke's disease
C. McArdle's disease
D. Down's syndrome

# All are true regarding glucose-6-phosphate deficiency except:
A. Hyperuricemia
B. Hyperglycemia
C. Defective cori cycle
D. Increased mobilization of glycogen from liver

# HMP shunt is of great importance in cellular metabolism because it produces:
A. ATP
B. ADP
C. Acetyl coA
D. NADPH

# Which of the following is not a product of HMP shunt?
A. NADPH
B. D fructose-6-phosphate
C. D sedoheptulose 5 phosphate
D. D glyceraldehyde 3 phosphate

# All these reactions take place inside the mitochondria except:
A. EMP pathway
B. Krebs cycle
C. Urea cycle
D. Electron transfer

# Number of ATP molecules generated in the conversion of glycogen to lactate is:
A. 2
B. 36
C. 38
D. 14

# One molecule of Acetyl co-A gives rise to ________ ATP molecules.
A. 2
B. 8
C. 12
D. 32

# The monosaccharide glucose is best described by which one of the following statements?
A. It usually exists in the fumarase form
B. It is a ketose
C. It possesses an anomeric C-2 carbon atom
D. It forms part of the disaccharide sucrose

# Which is not an oligosaccharide sugar?
A. Galactose
B. Lactose
C. Maltose
D. Sucrose

# Fructose intolerance is to:
A. Fructose only
B. Fructose and glucose
C. Sucrose only
D. Fructose and Sucrose

# Glycogen breakdown leads to formation of:
A. Glucose
B. Lactic acid
C. Glucose and Lactic acid
D. Glycoprotein

# Dietary fiber is rich in:
A. Starch
B. Cellulose
C. Collagen
D. Inulin

# Increase in pyruvate and lactate is seen in which of the following deficiency?
A. Thiamine
B. Pyridoxine
C. Niacin
D. Vitamin C

# Type II glycogen storage disorder is due to deficiency of:
A. alpha glucosidase
B. alpha galactosidase
C. Muscle phosphorylase
D. Acid Lipase

# Which one of the following enzymes provides a link between glycolysis and the citric acid cycle?
A. Lactate dehydrogenase
B. Pyruvate kinase
C. Citrate synthase
D. Pyruvate dehydrogenase

# Which of the following is most lipogenic?
A. Fructose
B. Glucose
C. Galactose
D. Ribose

# The uptake of glucose by the liver increases following a carbohydrate meal because:
A. There is increase in phosphorylation of glucose by glucokinase
B. GLUT-2 is stimulated by insulin
C. Glucokinase has a low Km for glucose
D. Hexokinase in liver has a high affinity for glucose

# Insulin increases the following pathways in liver EXCEPT:
A. Fatty acid synthesis
B. Glycogen synthesis
C. Protein synthesis
D. Glucose synthesis

# The citric acid cycle is the final pathway for the oxidation of:
A. Enzymes
B. Vitamins
C. Minerals
D. None of the above

# Acetyl coA can be converted into all of the following EXCEPT:
A. Glucose
B. Fatty acid
C. Cholesterol
D. Ketone bodies

# A patient with hereditary fructose intolerance is deficient in which of the following enzymes?
A. Aldolase
B. Fructokinase
C. Triokinase
D. All of the above

# Which of the following is not a monosaccharide?
A. Glucose
B. Galactose
C. Maltose
D. Fructose

# Substance for gluconeogenesis is:
A. Glycogen
B. Acetyl coA
C. Glycerol
D. Leucine

# Xylitol is a :
A. Natural sweet amino acid
B. Synthetic sweet amino acid
C. Natural five carbon sugar
D. Synthetic five carbon sugar

# Glucose transporters present in the B cells of the Islets of Langerhans are:
A. GLUT1
B. GLUT2
C. GLUT3
D. GLUT4