Contraindication for splenectomy

# Which out of the following is a contraindication for splenectomy ?
A. Iatrogenic splenic rupture
B. Thrombocytopenia
C. Presence of bone marrow failure
D. Hairy cell leukemia

The correct answer is C. Presence of bone marrow failure.

The only contraindication to splenectomy is the presence of marrow failure, in which the

enlarged spleen is the only source of hematopoietic tissue.

Ref: Harrison’s 18th Ed. 471