Nikolsky’s sign is a feature of:

 # Nikolsky’s sign is a feature of:

A. Lichen planus

B. Pemphigus

C. Herpes simplex

D. Lupus erythematosus

The correct answer is B. Pemphigus.

Nikolsky’s sign: It was named after Pytor Vasilyenich Nikolsky who was the first to describe this finding. On applying gentle mechanical pressure (e.g. blowing air or applying pressure with a mirror handle) on affected tissue will result in the formation of a lesion. Nikolsky’s sign is seen both in the skin and oral mucosa. It is seen in pemphigus, paraneoplastic pemphigus, mucous membrane pemphigoid, epidermolysis bullosa, linear IgA bullous disease, lupus erythematosus, graft-versus-host disease and toxic epidermal necrolysis.

Ref: Textbook of Oral Medicine, Oral Diagnosis and Oral Radiology,Ongole and Praveen, 2nd Edition, Page no. 235

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