Which of the following can be given safely in pregnancy?

 # Which of the following can be given safely in pregnancy? 

a. Imatinib 

b. Heparin 

c. Warfarin 

d. Thalidomide

The correct answer is B. Heparin.

Human Teratogenic Drugs - Drugs causing human birth defect

Thalidomide – Phocomelia, multiple defects

All anticancer drugs – Multiple defects, fetal death

Androgens – Virilization, limb, esophageal, cardiac defects

Progestins – Virilization of female fetus

Tetracycline – Discolored and deformed teeth, retarded bone growth

Warfarin – Nose, eye and hand defects, growth retardation

Phenytion – Hypoplastic phalanges, cleft lip/palate microcephaly

Phenobarbitone – Various malformations

Chlorpromazine – Neural tube defects

Valproate sodium – Spina bifida and other normal tube defects

Lithium – Fetal goitre, cardiac and other abnormalities

Isotretinoin – Craniofacial, heart and CVS defects

Imatinib – Multiple defects exomphalos, kidney abnormalities

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