# Chemotherapeutic agent has following side effects EXCEPT:
A. Hair loss
B. Diarrhoea
C. Hypertension
D. Mucositis
The correct answer is C. Hypertension.
Majority of the cytotoxic drugs have more profound effect on rapidly multiplying cells, because the most important target of action are the nucleic acids and their precursors, and rapid nucleic acid synthesis occurs during cell division. Many cancers (especially large solid tumours) have a lower growth fraction (lower percentage of cells are in division) than normal bone marrow, epithelial linings, reticuloendothelial (RE) system and gonads. These tissues are particularly affected in a dose-dependent manner by majority of drugs; though, there are differences in susceptibility to individual members.
KD Tripathi Page 859, 7th Edition
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