Exfoliative cytology is mainly used in the definitive diagnosis of the:

 # Exfoliative cytology is mainly used in the definitive diagnosis of the:

A. Oral cancer

B. Fungal infection

C. Vesiculobullous diseases

D. Viral infection

The correct answer is C. Vesiculobullous diseases.

It has been recognized that the exfoliative oral cytologic smear is also of value in the diagnosis of diseases other than carcinoma, particularly diseases which are characterized by the presence of certain specific cells. Thus, cytologic smears have been useful in the diagnosis of lesions of herpes simplex infection, herpes zoster, pemphigus vulgaris, benign familial pemphigus, keratosis follicularis, hereditary benign intraepithelial dyskeratosis, white sponge nevus, and pernicious and sickle cell anemia.

Reference: Shafer’s Textbook of ORAL PATHOLOGY, 7th Edition, Page No: 597

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