The potency of the midazolam is:

 # The potency of the midazolam is:

A. Thrice that of diazepam

B. Twice that of diazepam

C. 10 times that of diazepam

D. 5 times that of diazepam

The correct answer is A. Thrice that of diazepam.

Midazolam This BZD is water soluble, nonirritating to veins, faster and shorter acting (t½ 2 hours) and 3 times more potent than diazepam. Fall in BP is somewhat greater than with diazepam. It is being preferred over diazepam for anaesthetic use: 1–2.5 mg i.v. followed by 1/4th supplemental doses. Also used for sedation of intubated and mechanically ventilated patients and in other critical care anaesthesia as 0.02–0.1 mg/kg/hr continuous i.v. infusion.

Reference: Essentials of Medical Pharmacology, Seventh Edition, KD Tripathi, Page 383

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