MCQs on General Pathology - Wound Healing and Repair

# Synthesis of DNA occurs in which phase of cell cycle?
A. Mitosis-M phase
B. Gap- G1 phase
C. Gap-G2 phase
D. Synthesis- S phase

# Correct sequence of cell cycle is:
A. G0-G1-S-G2-M
B. G0-G1-G2-S-M
C. G0-M-G2-S-G1
D. G0-G1-S-M-G2

# Why fetal cells continue to divide but terminally differentiated adult ones do not divide?
A. Presence of cyclin inhibitors
B. Phosphatase absent in fetal cells
C. Proteinase is absent in fetus
D. Absence of CD kinase in adults

# The forming cells of which of the dental tissues is lost once the tissue is formed?
A. Enamel
B. Dentin
C. Periodontium
D. Cementum

# The proliferative capacity of bone and cartilage cells is described as:
A. Little proliferative capacity
B. Good proliferative capacity
C. Moderate proliferative capacity
D. No proliferative capacity

# The proliferative capacity of endothelial cells compared to cartilage cells is:
A. Great proliferative capacity
B. Same proliferative capacity
C. Poor proliferative capacity
D. No proliferative capacity

# The organ with maximum regenerative capacity:
A. Liver
B. Kidney
C. Brain
D. Pancreas

# Which of the following has least regenerative capacity?
A. Liver parenchyma
B. Cardiac muscle
C. Bone marrow
D. Vascular and fibrous connective tissue

# The first event in primary wound healing is:
A. Formation of blood clot
B. Acute inflammatory response
C. Epithelial changes
D. Organization of vascular and inflammatory cells

# All of the following events are common to primary wound healing and secondary wound healing EXCEPT:
A. Formation of blood clot
B. Inflammatory phase
C. Epithelial changes
D. Wound contraction

# Which of the following facilitates wound healing?
A. Exposure to ionising radiation
B. Exposure to UV light
C. Poor blood supply to the wound site
D. Presence of foreign body particles

# The persistence of epithelial cells after wound healing may give rise to:
A. Implantation cyst
B. Cicatrisation
C. Keloid formation
D. None of the above

# Keloid scars:
A. Usually occur in the caucasian race
B. Often occur in wounds which have healed perfectly without complications
C. Surgical treatment as a single modality has the least recurrence
D. Radiation should not be administerd as it is a non malignant condition

# The strength of a healing wound depends upon:
A. Formation of collagen fibres
B. Tissue growth factors
C. Hormones which increase wound healing
D. Adequate blood supply

# Which of the following hormones inhibits wound healing to a great extent?
A. Glucocorticosteroids
B. ADH
C. Growth hormone
D. Oestrogen

# Healing of wounds is retarded by:
A. Proteins
B. Cortisol
C. UV light
D. Vitamin C

# The cells which have the capacity to multiply throughout their life:
A. Labile cells
B. Stable cells
C. Permanent or fixed cells
D. None of the above

# Wounds which are clean and uninfected, surgically incised with edge of wounds approximated by sutures, heal by:
A. Primary intention
B. Secondary intention
C. Cicatrization
D. Regeneration

# Large open wounds that are characterized by loss of tissue and repaired by formationof granulation tissues in the floor of the wound is characteristic feature of:
A. Primary healing
B. Secondary healing
C. Cicatrization
D. Regeneration

# Which of the following heals by secondary intention?
A. Gingivectomy
B. Gingivoplasty
C. Extraction socket
D. All of the above

# An open extraction of a first molar is done and the sutures were given to approximate the buccal and lingual flap across the extraction site. The type of wound healing involved is:
A. Primary intention only
B. Secondary intention only
C. Both primary and secondary intention
D. None of the above

# Incomplete fractures of bone are called:
A. Green stick fractures
B. Simple closed fractures
C. Comminuted fractures
D. Compound fractures

# Bony union taking place with formation of medullary callus without periosteal callus formation (procallus) is seen in:
A. Primary union of fractures
B. Secondary union of fractures
C. Both primary and secondary union
D. None of the above

# Which of the following is not desirable during favorable union of fractured bones?
A. Formation and organization of hematoma during initial stages
B. Formation of procallus and osseous callus
C. Osteoclastic and osteoblastic remodelling of bone
D. Formation of fibrous joint or pseudoarthrosis

# Early ambulation, extensive bone necrosis and slow healing are features of which type of bone healing?
A. Primary union
B. Secondary union
C. Both of the above
D. Tertiary union

# Regeneration is maximum in what types of peripheral nerve degeneration?
A. Wallerian degeneration
B. Axonal degeneration
C. Segmental degeneration
D. All of them equally

# Stem cell research refers to:
A. The growth of human cells grown in vitro
B. The growth of human cells in other animals
C. The growth of cadaver cells in living humans
D. All of the above