# Matrix vesicles are derived from:
A. Elastin fibres
B. Collagen
C. Osteoblast
D. Inflammatory cells
The correct answer is C. Osteoblast.
The term matrix vesicles (MV) refers to small (20-200 nm) spherical bodies observed in the pre-mineralized matrix of dentin, cartilage and bone. They appear to be bounded by a lipid bilayer, and are often found associated with small crystals of calcium phosphate mineral. They are derived from the plasma membrane of mineral forming cells i.e. chondrocytes, osteoblasts, odontoblasts. The matrix vesicles promotes the formation of apatite by increasing the concentration of alkaline phosphatase that play a role in calcification.
Reference: Orban's
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