Crepitus will be seen in the tissues surrounding an infection by:

 # Crepitus will be seen in the tissues surrounding an infection by:

A. Staphylococcus

B. Streptococcus

C. Clostridium tetani

D. Clostridium perfringes

The correct answer is D. Clostridium perfringes. 

■ Clostridium perfringens causes gas gangrene or myonecrosis. 

■ Gas gangrene is characterized by skin colour change from pallor to bronze/purple discoloration and the skin is tense and exquisitely tender. 

■ Gas in the tissues may be obvious with crepitus on clinical examination or visible on radiograph. 

■ Surgical debridement, antibiotic therapy with high-dose I.V penicillin, clindamycin and metronidazole and hyperbaric oxygen therapy are used for treating gas gangrene [Note: Hyperbaric oxygen therapy is also used for osteoradionecrosis and chronic osteomyelitis]. 

■ Cl. tetani causes tetanus and cl. difficile causes pseudomembranous colitis.