# Histochemical demonstration of glycogen in the cells can help in the diagnosis of:
a) Malignant melanoma
b) Squamous cell carcinoma
c) Kaposi's sarcoma
d) Ewing's sarcoma
The correct answer is D. Ewing's sarcoma.
Ewing's sarcoma also called round cell sarcoma, seen in children and young adults, is characterized by painful swelling of the involved bone, facial neuralgia and lip paresthesia. It produces an irregular diffuse radiolucency, onion-skin and sun ray appearance of bone. Histologically, the neoplasm is composed of solid sheets of round cells, arranged in Filigree pattern. Intracytoplasmic glycogen of these cells helps in the differentiation from reticulum cell sarcoma.
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