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Syndrome in which all patients look similar, without being genetically linked to each other is:

 # Syndrome in which all patients look similar, without being genetically linked to each other is:
A. Hereditary ectodermal dysplasia
B. Von Recklinghausen
C. Gardner syndrome
D. Rosenthal syndrome


The correct answer is A. Hereditary ectodermal dysplasia. 

Hereditary ectodermal dysplasia is a large, heterogeneous group of inherited disorders involving skin, hair, nails, eccrine glands, and teeth. It is characterized by hypohidrosis, hypodontia, onychodysplasia, and hypotrichosis. Typical facies are characterized by frontal bossing, sunken cheeks, saddle nose, thick, everted lips, wrinkled hyperpigmented skin around the eyes, and low-set ears. Other common signs are short stature, eye abnormalities, decreased flow of tears, and photophobia. Since most of the signs are common, they resemble each other. 

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