MCQs in General Pathology - Acute and Chronic Infections

# Adenopathy is clinically manifested by:
A. Hyposalivation
B. Swelling
C. High grade fever
D. All of the above

# Lepra cells are seen in abundance in:
A. Tuberculoid leprosy
B. Lepromatous leprosy
C. Histoid leprosy
D. Intermediate leprosy

# Leonine face is seen in which type of leprosy?
A. Tuberculoid
B. Lepromatous
C. Borderline
D. Intermediate

# Early positive reaction in lepromin test is:
A. Fernandez reaction
B. Mitsuda reaction
C. Wasserman reaction
D. Non of the above

# In which of the following systems ascending infections are common?
A. Cardiac system
B. Urinary tract
C. Respiratory tract
D. Gastrointestinal tract

# Bacteremia is common following:
A. Root canal treatment
B. Pulpectomy
C. Scaling
D. Multiple extractions

# A bacterial disease with oropharyngeal manifestations:
A. Herpetic stomatitis
B. Diphtheria
C. Mumps
D. Measles

# Which of the following viruses is not dermotrophic?
A. Herpes
B. Polio
C. Rubeola
D. Rubella

# Serious complications of an infant delivered by a mother with gonorrhoea is:
A. Opthalmia neonatorum
B. Toxaemia
C. Congenital gonorrhoea
D. All of the above

# The enzymes liberated by streptococci which results in spread of infection is:
A. Polypeptides
B. Proteolytic enzymes
C. Fibrinolysin and hyaluronidase
D. None of the above

# Perivascular accumulation of monocytes (cell immunity) is not seen in:
A. Scarlet fever
B. Syphilis
C. Rabies
D. Herpes

# Anterior horns of spinal cord are damaged by:
A. Rabies
B. Poliomyelitis
C. Bacterial meningitis
D. All of the above

# Histologically, Koplik spots contain:
A. Intracytoplasmic inclusions
B. Intercytoplasmic inclusions
C. Both of the above
D. Inclusion bodies

# Which of the following are correctly matched?
A. Primary syphilis - 3-4 days after incubation
B. Secondary syphilis - 2-3 months after infection
C. Tertiary syphilis - Only after a latent period
D. All of the above

# The most infective lesion in which anerobic motile spirochetes can be demonstrated is:
A. Gumma
B. Mucous patch
C. Chancre
D. All of the above

# Which of the following is true of leutic aneurysm (syphilitic aneurysm)?
A. Common in aorta
B. There is classic tissue destruction
C. Weakening of tunica media results
D. All of the above

# The tertiary lesions of syphilis:
A. Form ulceration
B. Form granulation tissue
C. Form cold abscesses
D. Undergo healing with scar formation

# Which of the following post-streptococcal diseases are autoimmune?
A. Impetigo and erysipelas
B. Glomerulonephritis and rheumatic fever
C. Pharyngitis and puerperal fever
D. Scarlet fever and erysipelas

# Interstitial pneumonia is caused by:
A. Virus and Rickettsia
B. Fungus and bacteria
C. Rickettsia and bacteria
D. Virus and bacteria

# All of the following are features of infectious mononucleosis EXCEPT:
A. Bence jones proteins in urine
B. Increased number of abnormal lymphocytes which agglutinate with sheep RBC
C. Elevated heterophile titre
D. Cervical lymphadenopathy and splenomegaly

# Frontal bossing, olympian brow, opera glass nose and moon's mulberry molars is seen in:
A. Tuberculosis
B. Congenital gonorrhoea
C. Congenital syphilis
D. Ricketts

# Frontal bossing, saddle nose and Hutchinson's triad is seen in:
A. Tuberculosis
B. Congenital gonorrhoea
C. Congenital syphilis
D. Leprosy

# Most common mode of transmission of tuberculosis is:
A. Inhalation
B. Ingestion
C. Inoculation
D. Skin

# Most common route of spread of tuberculosis is:
A. Local spread
B. Lymphatics
C. Hematogenous
D. Natural passages

# Miliary tuberculosis is characterized by:
A. Hematogenous spread
B. Disseminated form involving many organs
C. Characterized by small caseating tubercle nodules
D. All of the above

# A massive large dose of tubercle bacilli compared to small dose produces:
A. No lesion
B. Non progressive lesion
C. Slowly progressing lesion
D. Latent period

# The pathological changes seen in tuberculosis are a result of:
A. Koch's phenomenon
B. Hypersensitivity and immunity
C. Acute inflammatory changes
D. Toxins liberated by bacteria

# A positive tuberculin test indicates:
A. Previous infection with tuberculous bacilli
B. Patient is susceptible to infection
C. Both of the above
D. None of the above

# Which of the following cells are seen in miliary tubercles?
A. Epitheloid cells in periphery of minute areas of caseation necrosis of granuloma
B. Eosinophils surrounding granuloma
C. Mast cells in centre of granuloma
D. Plasma cells in periphery of granuloma

# Cold abscess is a characteristic feature of:
A. Tuberculosis
B. Syphilis
C. Acute infective suppuration
D. All of the above

# Which of the following statements is correct?
A. Tuberculosis in man is caused by M. hominis and M. bovine
B. Bovine tuberculosis is least fatal compared to hominis
C. In AIDS common form of tuberculosis is M. avium intracellulare
D. All of the above

# Which of the following is least involved in secondary tuberculosis?
A. Lung
B. Intestine
C. Skin
D. Skeletal muscle

# Primary tuberculosis in children who has not been previously infected or immune is called as:
A. Ghon's complex
B. Pulmonary tuberculosis
C. Miliary tuberculosis
D. None of the above

# Ghon complex of the lung usually:
A. Undergoes cavitation
B. Undergoes calcification
C. Progresses to tuberculous pneumonia
D. Progresses to miliary tuberculosis

# The last stage of progressive tuberculosis lesion is:
A. Granuloma formation
B. Caseous necrosis
C. Cavitation
D. Calcification

# The hematogenous spread of tuberculosis infection from primary complex to the apex of lung as seen in secondary tuberculosis is called as:
A. Ghon's focus
B. Simon's focus
C. Miliary tuberculosis
D. None of the above

# Fibrocaseous tubercles are:
A. Hard tubercles
B. Soft tubercles
C. Calcified tubercles
D. Centrally liquefied tubercles

# Pulmonary tuberculosis is associated with all of the following EXCEPT:
A. Ghon's focus, at the junction of upper and lower lobes of lung
B. Lymph node components especially hilar lymph nodes with tuberculous granulation and fibroma
C. Pulmonary apical lesion
D. Ghon's tubercle or primary tubercle at the point of their entry into body

# Calcification of primary tubercles indicate:
A. Favorable healing response
B. Dissemination of caseous material
C. Reactivation of tuberculous bacillus
D. All of the above

# Granuloma with central caseation necrosis with cherry appearances (soft tubercle) is a feature of:
A. Tuberculosis
B. Sarcoidosis
C. Leprosy
D. All of the above

# The common causative organism in tuberculosis in AIDS patients is:
A. Mycobacterium hominis
B. M. bovis
C. M. avium intracellulare
D. M. murine

# Occupational disease of lung caused by inhalation of sugarcane dust is called as:
A. Byssinosis
B. Bagassosis
C. Anthracosis
D. Silicosis