Salivary gland aplasia is seen in:

 Salivary gland aplasia is seen in:

A. Hemifacial microsomia

B. LADD syndrome

C. Mandibulofacial dysostosis (Treacher Collins)

D. All of the above

The correct answer is D. All of the above.

Aplasia occurs for unknown reasons as an isolated finding or in conjunction with other developmental defects such as hemifacial microsomia, the LADD syndrome and mandibulo-facial dysostosis (Treacher Collins). In the more severe cases, the ensuing xerostomia causes clinical problems. Salivary loss leads to increased caries, burning sensations, oral infections, taste aberrations and difficulty with denture retention.