# Stain used to diagnose premalignant lesions of lip is:
A. Crystal violet
B. Giemsa
C. H and E
D. Toluidine blue
The correct answer is: D. Toluidine blue
Explanation:
Toluidine blue is a metachromatic dye that stains acidic tissue components and is commonly used to identify premalignant and malignant lesions. It has an affinity for DNA and RNA, highlighting areas of increased nuclear activity, such as dysplastic or malignant cells. This makes it particularly useful in diagnosing premalignant lesions of the lip and oral mucosa.
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