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The patient has a nasal fracture. What will be the test for confirmation of CSF leakage?

 # The patient has a nasal fracture. What will be the test for confirmation of CSF leakage?
A. CT scan 
B. Decreased glucose
C. Increased glucose
D. Transferrin beta


The correct answer is: D. Transferrin beta

Explanation:
Beta-2 transferrin is a specific marker for cerebrospinal fluid (CSF). It is not found in blood, nasal mucus, or other bodily fluids, making it a reliable test for confirming CSF leakage in cases like nasal fractures or head trauma.

Other options:

  • A. CT scan: Useful for identifying fractures or other structural damage but not specific for confirming CSF leakage.
  • B. Decreased glucose: Not a specific marker; glucose levels in nasal secretions can vary for other reasons.
  • C. Increased glucose: Similarly nonspecific; glucose levels alone are not definitive for detecting CSF leakage.

Note: CSF leakage is often suspected if clear fluid drains from the nose (rhinorrhea) or ears (otorrhea), especially after trauma. Beta-2 transferrin testing is the gold standard for confirmation.

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