Which one of the following drug does not cause gingival hyperplasia?

 # Which one of the following drug does not cause gingival hyperplasia?

A. Cyclosporine

B. Phenytoin

C. Phenobarbital

D. Nifedipine

The correct answer is: C. Phenobarbital

Explanation:

Gingival hyperplasia is a common side effect of certain drugs due to their impact on fibroblast activity and collagen metabolism.

• Cyclosporine: An immunosuppressant commonly associated with gingival hyperplasia.
• Phenytoin: An antiepileptic drug that frequently causes gingival overgrowth.
• Nifedipine: A calcium channel blocker linked to gingival hyperplasia, especially in patients with poor oral hygiene.
• Phenobarbital: An antiepileptic and sedative-hypnotic drug that does not typically cause gingival hyperplasia.