BPKIHS First Year BDS past Question- UNIT 1 - March 2014

21st MAR 2014

B.P. Koirala Institute of Health Sciences, Dharan, Nepal

1st year BDS

Internal Assessment Examination, March 2014

Paper - II A

(GENETICS, GROWTH AND DEVELOPMENT, IMMUNOLOGY & BLOOD)

Time - 2 Hours

 Total Marks: 125

SHORT ANSWER QUESTIONS

SECTION - 'A'

ANATOMY 

1. Classify chromosomal disorders with examples of each.                        5
2. Draw a labeled histological diagram of lymph node.                              5
3. Write the criteria and examples of X-linked recessive disorder.             5


                                                                    SECTION - 'B'
PHYSIOLOGY

4. State Landsteiner's law. Explain Rh and ABO blood group on the basis of this law.      2+2=4

5. With the help of flow diagram, explain the extrinsic pathway in blood coagulation.      4
6. Explain the role of erythropoietin in red blood cells production.       4
7. Draw the general, somatic and neural growth curves and briefly compare their patterns.     4
8. Explain the role of cytotoxic T cell in cellular immunity.              4

SECTION 'C'

BIOCHEMISTRY

9. Define the terms isotypes, idiotypes and allotypes.  Draw a labeled diagram of immunoglobulin.      3+2=5
10. Write similarities and differences between the processes of DNA and RNA synthesis.      5
11. Enumerate different post-translational modifications of polypeptide chain. Explain the function of chaperones.              3+2=5
12. Describe the mechanism of gene regulation with the help of lac operon model.          5
13. Explain how polymerase chain reaction (PCR) helps to amplify a target sequence of DNA.     5
14. Explain with a diagram mechanism of  iron absorption in the intestine.         5

SECTION 'D'

PATHOLOGY

15. Enumerate the types of Hypersensitivity reactions. Give at least two examples for each. Write briefly about type II hypersensitivity reaction.          2+1+2=5

16. Enumerate the types of blood components. What are the immediate and delayed blood transfusion reactions.         2+4 =6

17. Describe the peripheral smear and bone marrow findings of Megaloblastic anemia.     5+3=8

18. Enumerate six differences between AML and ALL.                                                     6

19. Classify Hemolytic Anaemia.                                                                                        5

SECTION 'E' 

MICROBIOLOGY

20. Draw a labeled diagram of HIV.                           5

21. Write short note on innate immunity.                   5

22. List the fungi causing opportunistic infection. Add a note on approach to lab diagnosis of any one of them.       2+3=5 

SECTION 'F'

PHARMACOLOGY

23. Explain warfarin effect in pregnancy.                 5

24. Explain Cyclophosphamide effect in urinary bladder.        5

25. Explain Cyclosporine effect in kidney.                               5

***

MCQs in Oral Pathology - Diseases of Microbial Origin

# Endotoxin is released from:
A. Candida albicans
B. Streptococcus sanguis
C. Gram negative bacteria
D. Actinomyces viscosus

# All of the following oral conditions can give rise to bacteremias, EXCEPT:
A. Extraction of tooth
B. Periodontitis
C. Endodontic therapy
D. Dentinal caries

# The most common extraoral cause of halitosis is:
A. Indigestion
B. Alcohol intake
C. Chronic sinusitis
D. Diabetes mellitus

# The typical triad of maxillary sinusitis are:
A. Nasal congestion, pathological secretion, Headache
B. Nasal congestion, trismus, epiphora
C. Nasal congestion, maxillary tooth pain, bloody discharge from the sinus
D. Nasal obstruction, headache, ear ache

Leutic Glossitis is caused by:

# Leutic glossitis is  an intraoral manifestation caused by:
A. Mycobacterium tuberculosis
B. Actinomycosis
C. Treponema pallidium
D. Streptococcus

The correct answer is C. Treponema pallidium. 

Leutic glossitis or syphilitic glossitis is atrophic or interstitial glossitis due to tongue involvement by treponema. The importance of leutic glossitis is the chance of undergoing malignant transformation.

Advantage of Digital Radiography

# One advantage of digital radiography is:
A. All the teeth can be in a single film
B.  Highly economical
C. The radiographic images are obtained immediately
D. Pulpal vitality can be accurately assessed

The correct answer is: C. The radiographic images are obtained immediately.

Advantages of digital radiography are:

- direct display of the image which is dynamic rather than static

- less patient exposure due to greater sensitivity

- Elimination of the need of darkroom

Studying the movements of the tongue:

# Which of the following is useful for studying the movements of the tongue?
A. Angiography
B. Arthroscope
C. Fluoroscope
D. Sonography

The correct answer is C. Fluoroscope.

FLUOROSCOPY IS REAL-TIME RADIOGRAPHY
. It allows continuous viewing of a time-varying X-ray image and permits live visual examination of dynamic events.

- Modern fluoroscopy systems use an X-ray image intensifier, which converts the X-ray energy into visible light and is coupled optically to a television camera.

- The fluoroscopic image is viewed on a cathode-ray tube video monitor, located either in the fluoroscopy room beside the patient, or else in a remote location.

MCQs on Pulp and Periapical Pathology

# Most cases of pulpitis are caused by:
A. Injudicious cavity preparation
B. Excessive heat incident to dry polishing of restorations
C. Bacterial invasion from a carious lesion
D. Bacterial invasion from the blood stream

# Odontalgia that is occasionally typical in hypertensive patients is a result of:
A. Headache radiating to the teeth
B. Nervous tension and worry
C. Hyperemia of pulp resulting from increased blood pressure
D. Abnormal situation of the sympathetic nerve system

MCQs on Virology - Microbiology MCQs

# A microorganism is described as smallest living organism, filterable submicroscopic and obligatory parasite. We are talking about:
A. Virus
B. Bacteria
C. Fungi
D. Protozoans

# Which of the following is characteristic only of viruses?
A. They are intracellular organisms
B. They affect the production of interferon and are sensitive to it
C. They reproduce by binary fission
D. They can be grown on an inanimate media

# Viruses can be isolated from clinical samples by cultivation in the following EXCEPT:
A. Tissue culture
B. Embryonated eggs
C. Animals
D. Chemically defined media

# All of the following are true for identification of viruses EXCEPT:
A. Nature of viral nucleic acid
B. Ability to be grown on differential media
C. Neutralisation with specific antisera makes antiviral vaccines a possibility
D. Nature of protein coat