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Contraindication for splenectomy

# Which out of the following is a contraindication for splenectomy ?
A. Iatrogenic splenic rupture
B. Thrombocytopenia
C. Presence of bone marrow failure
D. Hairy cell leukemia


The correct answer is C. Presence of bone marrow failure.

The only contraindication to splenectomy is the presence of marrow failure, in which the
enlarged spleen is the only source of hematopoietic tissue.

Ref: Harrison’s 18th Ed. 471

Weight of Normal Spleen

# Weight of a normal spleen is ?
A. < 150 grams
B. < 250 grams
C. < 350 grams
D. < 450 grams


The correct answer is B. < 250 grams.

Normal spleen weighs <250 grams.
Ref: Harrison’s 18th Ed. 468

Enlarged, grayish yellow or orange tonsils are pathognomic of

# Enlarged, grayish yellow or orange tonsils are pathognomic of ?
A. Waldenström’s macroglobulinemia
B. Polycythemia vera
C. Wolman disease
D. Tangier disease



The correct answer is D. Tangier Disease.

Tangier disease is associated with cholesterol accumulation in reticuloendothelial system with
hepatosplenomegaly & enlarged, grayish yellow or orange tonsils.

Ref: Harrison’s 18th Ed. 3154

Preauricular lymphadenopathy

# Preauricular lymphadenopathy accompanies which of the following?
A. Scalp infection
B. Ear infection
C. Conjunctival infections
D. Tooth infection




The correct answer is: C. Conjunctival infections.

Preauricular adenopathy accompanies conjunctival infections and cat-scratch disease.

Ref: Harrison’s 18th Ed. 466