Histopathological feature of basal cell carcinoma

# Characteristic histopathological feature of basal cell carcinoma is:
a) Nuclear palisading
b) Keratin pearls
c) Psammoma bodies
d) Foam cells

The correct answer is A. Nuclear palisading.

• In nodular basal cell carcinoma, the tumor cells typically have large, hyperchromatic, oval nuclei with little cytoplasm and nests of tumor cells show peripheral cell palisading.

• Keratin pearls are found in squamous cell carcinoma, while Psammoma bodies are concentric lamellated structures found in papillary thyroid carcinoma, meningioma, papillary serous cystadenocarcinoma of the ovary.

• Foam cells are found in verruciform xanthoma.

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Granularity of oncocytes

# Granularity of oncocyte is due to:
a) Overabundance of golgi bodies
b) Overabundance of mitochondria
c) Deficiency of mitochondria
d) Deficiency of golgi bodies

The correct answer is B. Overabundance of mitochondria.

Oncocytoma is a rare benign salivary gland tumor composed of oncocytes with granular eosinophilic cytoplasm and a large number of atypical mitochondria. The name oncocytoma is derived from the resemblance of these tumor cells to apparently normal cells termed oncocytes found in salivary glands, respiratory tract, breast, thyroid, pancreas, parathyroid, pituitary, testicle, fallopian tube, liver and stomach. Electron microscopic studies have shown that cytoplasm of oncocyte is choked with mitochondria.

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Sturge Weber Syndrome

# Sturge Weber syndrome is characterized by all EXCEPT:
a) Exophytic oral hemangioma
b) Facial hematoma
c) Tramline calcification of dura on lateral cephalogram
d) Facial hemangioma

The correct answer is B. Facial hematoma.


Though the skin and oral lesions of hemangioma are most deforming and disfiguring, the CNS involvement often results in serious problems of epilepsy, hemiplegia, mental retardation and retinal changes. Sturge-weber syndrome is probably the most common of these malformations. It is characterized by angiomatosis of face, laptomeningeal angiomas, contralateral hemiplegia, massive gingival growths and asymmetric jaw growth. The patients are treated for many years with phenytoin.

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Most common site of Oral Leukoplakia

# Most common site of oral leukoplakia is :
a) angle of mouth
b) cheek mucosa
c) Soft palate
d) Gingiva

The correct answer is B. Cheek mucosa.

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Standard airway for Ludwig's Angina

# Standard Airway for Ludwig's Angina is: a) Tracheotomy
b) Cricothyrotomy
c) Nasal intubation
d) Oral intubation

The correct answer is B. Cricothyrotomy.

In Ludwig's angina, cricothyrotomy is always preferred over option A, i.e., Tracheotomy. Tracheotomy is avoided because of the following reasons.
• Identification of landmarks is difficult due to associated massive edema and tissue distortion.
• Sometimes, tracheostomy may lead to spread of infection to deeper tissues.
• May result in Tracheal stenosis in 25 -50% of cases.
• Chances of getting pneumonia will always be there.
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Trotter's Triad

# Trotter's triad is seen in:
a) Angiofibroma
b) Nasopharyngeal carcinoma
c) Laryngeal carcinoma
d) Growth in fossa of Rosenmuller

The correct answer is B. Nasopharyngeal carcinoma.

Trotter's triad:
1) Conductive deafness (Eustachian tube blockade)
2) lpsilateral temporoparietal neuralgia (Cranial Nerve V)
3) Palatal paralysis (Cranial Nerve X)

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Nasopharyngeal carcinoma virus

#The virus associated with nasopharyngeal carcinoma is:
a) Epstein Barr
b) Cytomegalo virus
c) Hepatitis
d) Herpes virus

The correct answer is A. Epstein Barr.

Nasopharyngeal carcinoma affects younger age group and half of the patients will present with secondaries in neck.

Epstein-Barr virus is also implicated as an etiological factor for Burkitts Lymphoma and infectious mononucleosis.

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