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Amyloidosis most commonly occurs in:

 # Amyloidosis most commonly occurs in:
A. Kidney
B. Spleen
C. Liver
D. Heart


The correct answer is A. Kidney.

Amyloidosis of the kidneys is most common and most serious because of ill effects on renal function. Kidneys affected by amyloidosis may be normal sized or enlarged; the cut surface is pale, waxy and translucent. Amyloidosis of spleen has two patterns - Sago spleen and lardaceous spleen. 

CSF rhinorrhea is found in:

 # CSF rhinorrhea is found in:
A. Frontal bone fracture
B. Zygomatico maxillary fracture
C. Nasoethmoidal fracture
D. Condylar fracture


The correct answer is C. Nasoethmoidal fracture.

CSF rhinorrhea is seen in nasoethmoidal, Le Fort II and Le Fort III fractures, associated with comminuted cibriform plate of ethmoid. Tramline effect and halo on pillow effect are diagnostic signs of CSF rhinorrhea. 


Wounds which are clean, uninfected and surgically incised, with edge of wounds approximated by sutures heal by:

 # Wounds which are clean, uninfected and surgically incised, with edge of wounds approximated by sutures heal by:
A. Primary intention
B. Secondary intention
C. Cauterization
D. All of the above


The correct answer is A. Primary intention.

Clean, uninfected, surgically incised wounds that are approximated by surgical sutures heal by primary intention. Infected, open large wounds that are not approximated by surgical sutures heal by secondary intention. Healing after flap surgery is by primary intention where as gingivectomy, gingivoplasty and extraction socket heal by secondary intention. 

Tensile strength of wound becomes normal after:

 # Tensile strength of wound becomes normal after:
A. 6 weeks
B. 4 month
C. 6 month
D. Never


The correct answer is D. Never.

Tensile strength of the scar is never equal to the original tissue, is always less (the maximum being 80% that of unwounded skin).

The best method of intubation for a child patient is:

 # A pediatric patient is brought to the clinic for interpositional arthroplasty procedure. The best method of intubation is:
A. Topical anesthesia and sedation
B. GA
C. Fibreoptic intubation
D. Tracheostomy



The correct answer is C. Fibreoptic intubation.

Nasal fibreoptic tube with cuffed endotracheal one size less than that is indicated for children is the best method. Airway management is either by oral airway or LMA. Inhalational induction should be done as paediatric patients cannot tolerate awake fibro-optic intubation. Usually uncuffed ETT are preferred in child patients. 

Thesis Topic Ideas for MDS Oral Pathology

Thesis and research is a part of MDS curriculum. Here are some good research topics to consider if you are an MDS Oral Pathology Resident.


  1. Molecular and genetic markers in the diagnosis and prognosis of oral squamous cell carcinoma.
  2. Role of immune checkpoint inhibitors in the management of oral cancer.
  3. Analysis of potential biomarkers for early detection of oral potentially malignant disorders.
  4. Evaluation of the association between human papillomavirus (HPV) and oral cancer.
  5. Molecular pathways involved in the development and progression of oral leukoplakia.
  6. Characterization of microRNA expression profiles in oral cancer and potentially malignant lesions.
  7. Impact of tobacco and betel quid on the molecular alterations in oral mucosal cells.
  8. Association between oral health and systemic diseases: A focus on inflammation and immune response.
  9. Evaluation of the expression of cancer stem cell markers in oral cancer.
  10. Role of exosomes in the communication between cancer cells and the tumor microenvironment in oral malignancies.
  11. Analysis of the molecular signature of oral lichen planus.
  12. Comparative study of different immunohistochemical markers in the diagnosis of salivary gland tumors.
  13. Expression of angiogenesis-related markers in oral cancer and potentially malignant disorders.
  14. Molecular profiling of oral submucous fibrosis for personalized therapeutic approaches.
  15. Evaluation of the role of tumor-infiltrating lymphocytes in the prognosis of oral cancer.
  16. Association between oral microbiota and the development of oral squamous cell carcinoma.
  17. Molecular mechanisms underlying the metastasis of oral cancer to regional lymph nodes.
  18. Analysis of epigenetic alterations in oral precancerous lesions and cancer.
  19. Expression of programmed death-ligand 1 (PD-L1) in oral squamous cell carcinoma and its clinical implications.
  20. Molecular characterization of odontogenic tumors: A focus on ameloblastoma and odontogenic myxoma.
  21. Role of liquid biopsy in monitoring disease progression and treatment response in oral cancer.
  22. Genetic mutations associated with familial forms of oral cancer.
  23. Expression patterns of tumor suppressor genes in oral potentially malignant disorders.
  24. Evaluation of the microenvironment in oral squamous cell carcinoma: Immune cell infiltration and stromal components.
  25. Molecular alterations in oral dysplastic lesions and their correlation with clinical outcomes.
  26. Analysis of the association between herpesviruses and the development of oral cancers.
  27. Identification of prognostic biomarkers in oral verrucous carcinoma.
  28. Molecular profiling of oral manifestations in patients with systemic autoimmune diseases.
  29. Expression of cancer-associated fibroblast markers in the stroma of oral squamous cell carcinoma.
  30. Comparative study of different diagnostic modalities in the evaluation of salivary gland tumors.
  31. Genetic polymorphisms and susceptibility to oral potentially malignant disorders.
  32. Role of tumor microenvironment in the chemoresistance of oral cancer.
  33. Analysis of the role of autophagy in the progression of oral cancer.
  34. Identification of novel therapeutic targets in the treatment of oral lichenoid reactions.
  35. Expression of DNA repair genes in oral premalignant and malignant lesions.
  36. Association between oral health and quality of life in patients with oral cancer.
  37. Molecular characterization of desmoplastic ameloblastoma.
  38. Genetic predisposition and risk factors for the development of oral leukoplakia.
  39. Expression of neuroendocrine markers in oral neuroendocrine tumors.
  40. Role of extracellular vesicles in intercellular communication in oral cancer.
  41. Analysis of genetic and epigenetic alterations in oral verrucous hyperplasia.
  42. Association between oral microbiome and oral potentially malignant disorders.
  43. Molecular profiling of oral melanoma for targeted therapy.
  44. Expression of stem cell markers in oral squamous cell carcinoma and its correlation with prognosis.
  45. Evaluation of the role of angiogenesis in the progression of oral verrucous carcinoma.
  46. Molecular mechanisms of drug resistance in oral cancer chemotherapy.
  47. Analysis of the tumor immune microenvironment in oral verrucous hyperplasia.
  48. Association between immune-related genetic markers and the development of oral lichen planus.
  49. Molecular characterization of salivary duct carcinoma.
  50. Role of exosomal miRNAs in the communication between cancer cells and the immune system in oral cancer.
  51. Analysis of the association between p53 mutations and clinical outcomes in oral cancer.
  52. Molecular profiling of recurrent oral squamous cell carcinoma.
  53. Expression of glycolysis-related markers in oral cancer and potentially malignant disorders.
  54. Association between dysregulated autophagy and oral premalignant lesions.
  55. Molecular characterization of oral metastatic lesions from distant primary tumors.
  56. Genetic mutations in oral epithelial dysplasia associated with malignant transformation.
  57. Expression of immune checkpoint molecules in oral potentially malignant disorders.
  58. Role of the Wnt signaling pathway in the development of ameloblastoma.
  59. Molecular characterization of oral verrucous hyperplasia associated with tobacco use.
  60. Association between oral microbial dysbiosis and the recurrence of oral cancer.
  61. Expression of epithelial-mesenchymal transition (EMT) markers in oral cancer.
  62. Molecular profiling of clear cell odontogenic carcinoma.
  63. Role of tumor-derived exosomes in immune evasion in oral cancer.
  64. Analysis of the association between oral health and the risk of developing oral squamous cell carcinoma.
  65. Molecular characterization of adenoid cystic carcinoma of the oral cavity.
  66. Expression of oncogenic viruses in oral verrucous carcinoma.
  67. Association between tumor-infiltrating lymphocytes and response to immunotherapy in oral cancer.
  68. Molecular profiling of oral carcinomas in young adults.
  69. Genetic and epigenetic alterations in oral basaloid squamous cell carcinoma.
  70. Role of immune-related genetic polymorphisms in the susceptibility to oral lichen planus.
  71. Analysis of the association between microRNA dysregulation and the development of oral cancer.
  72. Molecular characterization of oral epithelial dysplasia associated with betel quid chewing.
  73. Expression of cancer stem cell markers in oral verrucous carcinoma.
  74. Association between human epidermal growth factor receptor 2 (HER2) expression and clinical outcomes in oral cancer.
  75. Molecular profiling of oral mucositis in cancer patients undergoing radiation therapy.
  76. Genetic alterations in oral verrucous hyperplasia associated with chronic inflammation.
  77. Role of circular RNAs in the regulation of gene expression in oral cancer.
  78. Analysis of the association between oral microbial composition and the risk of oral leukoplakia.
  79. Molecular characterization of peripheral ameloblastoma.
  80. Expression of immune checkpoint molecules in salivary gland tumors.
  81. Association between genetic polymorphisms and the susceptibility to oral submucous fibrosis.
  82. Analysis of the tumor microenvironment in oral verrucous hyperplasia associated with human papillomavirus infection.
  83. Molecular profiling of primary and recurrent oral squamous cell carcinoma.
  84. Expression of glycosylation-related markers in oral potentially malignant disorders.
  85. Role of autophagy in the response to radiation therapy in oral cancer.
  86. Association between oral microbial dysbiosis and the recurrence of oral potentially malignant disorders.
  87. Molecular characterization of oral mucoepidermoid carcinoma.
  88. Genetic mutations associated with the development of oral lichenoid reactions.
  89. Expression of immune checkpoint molecules in oral epithelial dysplasia.
  90. Role of long non-coding RNAs in the regulation of gene expression in oral cancer.
  91. Analysis of the association between telomere length and the progression of oral potentially malignant disorders.
  92. Molecular profiling of oral carcinoma ex pleomorphic adenoma.
  93. Association between genetic polymorphisms and the risk of developing oral verrucous carcinoma.
  94. Expression of cancer-associated fibroblast markers in oral epithelial dysplasia.
  95. Role of circular RNAs in the regulation of immune responses in oral cancer.
  96. Analysis of the association between p16 expression and clinical outcomes in oral cancer.
  97. Molecular characterization of oral granular cell tumors.
  98. Genetic alterations in oral potentially malignant disorders associated with immune response.
  99. Expression of immune checkpoint molecules in oral verrucous hyperplasia.
  100. Role of tumor-derived exosomes in the modulation of immune responses in oral cancer.
There are several important things to consider before finalizing your thesis topic. Some of the key factors to keep in mind include:

Interest: You should choose a topic that you are passionate about and find interesting. This will help you stay motivated throughout the research and writing process.

Feasibility: You should choose a topic that is feasible given the resources, time, and expertise available to you. Consider the scope of the project and the feasibility of collecting data.

Significance: You should choose a topic that is significant and relevant to your field of study. The research should add value and contribute to the existing knowledge in the field.

Originality: You should choose a topic that is original and has not been extensively researched before. Your research should aim to contribute new insights and knowledge to the field.

Clarity: You should have a clear research question or hypothesis that can guide your research. The topic should be specific and focused to ensure that you can conduct a thorough investigation.

Accessibility: You should have access to the necessary data, resources, and materials required to conduct your research. Ensure that you have the necessary permissions and approvals to collect data and conduct your research.

Advisor's approval: It is important to seek feedback and guidance from your thesis advisor before finalizing your topic. They can provide valuable insights and help you choose a topic that aligns with your interests and goals.

By considering these factors, you can select a topic that aligns with your interests, is feasible, significant, original, clear, accessible, and approved by your advisor.

Thesis Topic Ideas for MDS Conservative Dentistry and Endodontics

Thesis and research is a part of MDS curriculum. Here are some good research topics to consider if you are an MDS Conservative Dentistry and Endodontics Resident.


  1. Comparative evaluation of different obturation techniques in root canal treatment.
  2. Analysis of the antimicrobial efficacy of various root canal irrigants.
  3. Impact of different instrumentation techniques on postoperative pain in endodontic therapy.
  4. Evaluation of the success rate of different intracanal medicaments in pulp vitality preservation.
  5. Comparative study of the antibacterial properties of root canal sealers.
  6. Assessment of the clinical outcomes of regenerative endodontic procedures.
  7. Analysis of the effect of different irrigation protocols on the removal of smear layer.
  8. Evaluation of the influence of root canal curvature on instrumentation efficacy.
  9. Comparative study of different obturation materials in terms of sealing ability.
  10. Assessment of the effectiveness of different diagnostic aids in identifying root canal anatomy.
  11. Impact of different irrigation solutions on the microhardness of root dentin.
  12. Evaluation of the bond strength of various endodontic sealers to root dentin.
  13. Comparative study of different techniques for root canal disinfection.
  14. Analysis of the effect of different intracanal medicaments on postoperative pain.
  15. Assessment of the impact of rotary and reciprocating instrumentation on canal transportation.
  16. Comparative evaluation of single-cone and cold lateral condensation techniques in obturation.
  17. Evaluation of the antimicrobial properties of calcium hydroxide as an intracanal medicament.
  18. Impact of different instrumentation systems on the shaping ability of root canals.
  19. Analysis of the influence of root canal anatomy on the success of endodontic therapy.
  20. Comparative study of the fracture resistance of endodontically treated teeth restored with different post systems.
  21. Evaluation of the effectiveness of laser therapy in disinfecting root canals.
  22. Assessment of the impact of different access cavity designs on the success of endodontic therapy.
  23. Comparative study of different obturation techniques in curved root canals.
  24. Analysis of the antimicrobial efficacy of ozonated water in root canal irrigation.
  25. Evaluation of the bond strength of different obturation materials to dentin.
  26. Impact of different irrigant activation techniques on debris removal in root canals.
  27. Comparative study of different pulp capping agents in vital pulp therapy.
  28. Assessment of the success rate of different apex locators in determining working length.
  29. Analysis of the influence of different irrigation systems on the preservation of apical dentin.
  30. Evaluation of the effect of different canal drying techniques on the bond strength of obturation materials.
  31. Comparative study of the antimicrobial efficacy of photoactivated disinfection in root canal treatment.
  32. Impact of different obturation materials on the fracture resistance of endodontically treated teeth.
  33. Assessment of the influence of different irrigant delivery systems on cleaning efficacy.
  34. Comparative evaluation of the antibacterial properties of silver nanoparticles in endodontic therapy.
  35. Analysis of the effect of different obturation techniques on the formation of voids.
  36. Evaluation of the success rate of different apexification techniques in immature teeth.
  37. Impact of different access cavity designs on the incidence of iatrogenic errors during root canal treatment.
  38. Comparative study of different regenerative endodontic protocols for immature teeth.
  39. Assessment of the impact of different obturation techniques on the adaptation of sealer to canal walls.
  40. Analysis of the effect of different irrigation solutions on the dissolution of pulp tissue.
  41. Evaluation of the bond strength of different resin-based sealers to dentin.
  42. Comparative study of the antimicrobial efficacy of herbal extracts in root canal disinfection.
  43. Impact of different obturation materials on the retreatability of root canal fillings.
  44. Assessment of the success rate of different root canal filling techniques in oval-shaped canals.
  45. Analysis of the influence of preoperative pain on postoperative discomfort in endodontic therapy.
  46. Comparative evaluation of different irrigation protocols in removing smear layer.
  47. Evaluation of the bond strength of different obturation materials to dentin treated with chelating agents.
  48. Impact of different intracanal medicaments on the bond strength of resin-based sealers.
  49. Assessment of the influence of different post systems on the fracture resistance of endodontically treated teeth.
  50. Comparative study of different obturation materials in the presence of simulated intracanal microorganisms.
  51. Analysis of the antimicrobial efficacy of probiotics in root canal disinfection.
  52. Evaluation of the success rate of different apexification techniques in necrotic immature teeth.
  53. Impact of different irrigation solutions on the removal of the smear layer in apical third.
  54. Comparative study of different obturation techniques in oval-shaped canals.
  55. Assessment of the bond strength of different obturation materials to root canal dentin treated with laser irradiation.
  56. Analysis of the influence of root canal curvature on the adaptation of obturation materials.
  57. Evaluation of the antimicrobial efficacy of ozone in root canal disinfection.
  58. Comparative study of different pulp capping agents in maintaining pulp vitality.
  59. Impact of different irrigation solutions on the removal of the smear layer in lateral canals.
  60. Assessment of the bond strength of different obturation materials to dentin treated with different irrigation solutions.
  61. Analysis of the effect of different post systems on the root canal filling adaptation.
  62. Evaluation of the success rate of different apexification techniques in teeth with open apices.
  63. Comparative study of different intracanal medicaments in root canal disinfection.
  64. Impact of different access cavity designs on the incidence of postoperative pain in endodontic therapy.
  65. Assessment of the influence of root canal curvature on the apical transportation caused by different instrumentation systems.
  66. Analysis of the antimicrobial efficacy of silver diamine fluoride in root canal disinfection.
  67. Comparative evaluation of different irrigation protocols in the removal of endotoxins from root canals.
  68. Evaluation of the bond strength of different obturation materials to radicular dentin.
  69. Impact of different intracanal medicaments on the push-out bond strength of fiber posts.
  70. Assessment of the success rate of different apexification techniques in teeth with large periapical lesions.
  71. Comparative study of different obturation materials in the presence of intracanal microorganisms.
  72. Analysis of the effect of different obturation techniques on the adaptation of gutta-percha to canal walls.
  73. Evaluation of the antimicrobial efficacy of chitosan nanoparticles in root canal disinfection.
  74. Impact of different irrigation protocols on the removal of endotoxins from root canals.
  75. Comparative study of the bond strength of different obturation materials to root canal dentin treated with ozone.
  76. Assessment of the success rate of different apexification techniques in teeth with open apices and large periapical lesions.
  77. Analysis of the influence of different access cavity designs on the incidence of canal transportation.
  78. Evaluation of the effect of different irrigation solutions on the removal of the smear layer in curved canals.
  79. Comparative evaluation of different obturation materials in the presence of simulated lateral canals.
  80. Impact of different intracanal medicaments on the bond strength of fiber posts.
  81. Assessment of the antimicrobial efficacy of nanoparticles in root canal disinfection.
  82. Analysis of the effect of different instrumentation techniques on the fracture resistance of endodontically treated teeth.
  83. Evaluation of the bond strength of different obturation materials to radicular dentin treated with laser irradiation.
  84. Comparative study of different obturation techniques in teeth with apical root resorption.
  85. Impact of different irrigation protocols on the removal of the smear layer in oval-shaped canals.
  86. Assessment of the success rate of different apexification techniques in teeth with open apices and thin radicular dentin.
  87. Analysis of the influence of different instrumentation systems on the fracture resistance of root-filled teeth.
  88. Evaluation of the effect of different irrigation solutions on the bond strength of resin-based sealers to dentin.
  89. Comparative study of the antimicrobial efficacy of herbal extracts in root canal disinfection.
  90. Impact of different obturation materials on the fracture resistance of teeth with apical root resorption.
  91. Assessment of the bond strength of different obturation materials to radicular dentin treated with chelating agents.
  92. Analysis of the effect of different obturation techniques on the apical sealing ability.
  93. Evaluation of the success rate of different apexification techniques in teeth with apical root resorption.
  94. Comparative study of the influence of different access cavity designs on the incidence of iatrogenic errors in root canal therapy.
  95. Impact of different irrigation protocols on the push-out bond strength of fiber posts.
  96. Assessment of the antimicrobial efficacy of silver nanoparticles in root canal disinfection.
  97. Analysis of the effect of different instrumentation techniques on the bond strength of resin-based sealers to dentin.
  98. Evaluation of the bond strength of different obturation materials to radicular dentin treated with different irrigation solutions.
  99. Comparative study of different obturation techniques in teeth with apical root resorption.
  100. Impact of different irrigation solutions on the apical sealing ability of root canal fillings.
There are several important things to consider before finalizing your thesis topic. Some of the key factors to keep in mind include:

Interest: You should choose a topic that you are passionate about and find interesting. This will help you stay motivated throughout the research and writing process.

Feasibility: You should choose a topic that is feasible given the resources, time, and expertise available to you. Consider the scope of the project and the feasibility of collecting data.

Significance: You should choose a topic that is significant and relevant to your field of study. The research should add value and contribute to the existing knowledge in the field.

Originality: You should choose a topic that is original and has not been extensively researched before. Your research should aim to contribute new insights and knowledge to the field.

Clarity: You should have a clear research question or hypothesis that can guide your research. The topic should be specific and focused to ensure that you can conduct a thorough investigation.

Accessibility: You should have access to the necessary data, resources, and materials required to conduct your research. Ensure that you have the necessary permissions and approvals to collect data and conduct your research.

Advisor's approval: It is important to seek feedback and guidance from your thesis advisor before finalizing your topic. They can provide valuable insights and help you choose a topic that aligns with your interests and goals.

By considering these factors, you can select a topic that aligns with your interests, is feasible, significant, original, clear, accessible, and approved by your advisor.